cathepsin inhibitor 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6015	Cathepsin Inhibitor 1		Cysteine Protease
	Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.		Cysteine Protease
TP1015	NFAT Inhibitor	VIVIT peptide	Others
	NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.		Others
T3088	N-Ethylmaleimide	1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM	Cysteine Protease , DUB
	N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.		Cysteine Protease , DUB
T60812	Cathepsin X-IN-1		Cysteine Protease
	Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].		Cysteine Protease
T6035	Odanacatib	MK-0822	Cysteine Protease
	Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.		Cysteine Protease
TJS2216	Aurantiamide acetate	Asperglaucide	Cysteine Protease
	Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...		Cysteine Protease
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T62659	Cathepsin C-IN-4
	Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
T80105	Z-Phe-Phe-Diazomethylketone
	Z-Phe-Phe-Diazomethylketone is a selective inhibitor of cathepsin L [1].
T72569	Cathepsin L/S-IN-1
	Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and inv...
T80740	Z-FG-NHO-Bz
	Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].
T81265	RKLLW-NH2
	RKLLW-NH2 is an inhibitor of the protease Cathepsin L [1].
T14187	ALLM	Calpain inhibitor II	Others
	ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].		Others
T41236	Z-FY-CHO
	Z-FY-CHO (Z-Phe-Tyr-CHO) is a specific and potent cathepsin L (CTSL) inhibitor [1] [2].
T80739	Z-FG-NHO-BzOME
	Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S, and papain [1].
T61413	Gü1303
	Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK). This compound effectively suppresses the autocatalytic activation of the CatK zymogen [1].
T63854	Cathepsin C-IN-3
	Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
T60838	Gü2602
	Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for mature CatK (mCatK) [1].
T78186	Ac-VLPE-FMK	Ac-Val-Leu-Pro-Glu(OMe)-CH2F
	Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), functions as an inhibitor of both Cathepsin B (Cat-B) and Cathepsin L (Cat-L), and is utilized in research pertaining to the aggressiveness of cancer [1] [2]...
T76599	Ac-Leu-Val-Lys-Aldehyde
	Ac-Leu-Val-Lys-Aldehyde is a potent inhibitor of cathepsin B, exhibiting inhibitory concentration (IC50) values of 4 nM. It notably diminishes cell death in the striatum induced by quinolinic acid and leads to the accumu...